Publications

  1. Dudok, B.*, Fan, L.Z.*, Farrell, J.S., Malhotra, S., Homidan, J., Kim, D.K., Wenardy, C., Ramakrishnan, C., Li, Y., Deisseroth, K., Soltesz, I., Retrograde endocannabinoid signaling at inhibitory synapses in vivo. Science, Accepted (2024). (* denotes equal contributions)
  2. Kim, S., Ko, G., Kang, I., Tian, H., Fan, L.Z., Li, Y., Cohen, A.E., Wu, J., Dai, Q., Choi, M.M. (2023). Optical segmentation-based compressed readout of neuronal voltage dynamics. bioRxiv, 2023-11. [Link]
  3. Fan, L.Z., Kim, D.K., Jennings, J.H., Tian, H., Wang, P.Y., Ramakrishnan, C., Randles, S., Sun, Y., Thadhani, E., Kim, Y.S., Quirin, S., Giocomo, L., Cohen, A.E., Deisseroth, K. (2023). All-optical physiology resolves a synaptic basis for behavioral timescale plasticity. Cell, 186(3), 543-559. [PDF] [Link]
  4. Tian, H., Davis, H.C., Wong-Campos, D.J., Park, P., Fan, L.Z., Gmeiner, B., Begum, S., Werley, C.A., Borja, G.B., Upadhyay, H., Shah, H., Jacques, J., Qi, Y., Parot, V.J., Deisseroth, K., Cohen, A.E. (2023). Video-based pooled screening yields improved far-red genetically encoded voltage indicators. Nature Methods, 1-13. [PDF] [Link]
  5. Xie, M.E., Adam, Y., Fan, L.Z., Böhm, U.L., Kinsella, I., Zhou, D., Rozsa, M., Singh, A., Svoboda, K., Paninski, L., Cohen, A.E. (2021). High fidelity estimates of spikes and subthreshold waveforms from 1-photon voltage imaging in vivo. Cell Reports, 35(1). [PDF] [Link]
  6. Fan, L.Z., Kheifets, S., Böhm, U.L., Wu, H., Piatkevich, K.D., Xie, M.E., Parot, V.J., Ha, Y., Evans, K.E., Boyden, E.S., Takesian, A.E., Cohen, A.E. (2020). All-optical electrophysiology reveals the role of lateral inhibition in sensory processing in cortical layer 1. Cell, 180(3), 521-535. [PDF] [Link]
    • Spotlight: Patil, P., and Yizhar, O. (2020). In Vivo Optophysiology Reveals Lateral Inhibition among Layer 1 Interneurons. Neuron, 106(1), 14-16.
  7. Parot, V.J., Sing-Long, C., Adam, Y., Böhm, U.L., Fan, L.Z., Farhi, S.L., Cohen, A.E. (2019). Compressed Hadamard Microscopy for high-speed optically sectioned neuronal activity recordings. Journal of Physics D: Applied Physics, 52(14), 144001. [PDF] [Link]
  8. Fan, L.Z., Nehme, R., Adam, Y., Jeung, E., Wu, H., Eggan, K., Arnold, D.B., Cohen, A.E. (2018). All-optical synaptic electrophysiology probes mechanism of ketamine-induced disinhibition. Nature Methods, 15(10), 823-831. [PDF] [Link]
  9. Zhou, X.X., Fan, L.Z., Li, P., Shen, K., Lin, M.Z. (2017). Optical control of cell signaling by single-chain photoswitchable kinases. Science, 355(6327), 836-842. [PDF] [Link]
  10. Ogden, K.K., Chen, W., Swanger, S.A., McDaniel, M.J., Fan, L.Z., Hu, C., Tankovic, A., Kusumoto, H., Kosobucki, G.J., Schulien A.J., Su, Z., Pecha, J., Bhattacharya, S., Petrovski, S., Cohen, A.E., Aizenman, E., Traynelis, S.F., Yuan, H. (2017). Molecular mechanism of disease-associated mutations in the pre-M1 helix of NMDA receptors and potential rescue pharmacology. PLoS Genetics, 13(1), e1006536. [PDF] [Link]
  11. Fan, L.Z., Lin, M.Z. (2015). Optical control of biological processes by light-switchable proteins. Wiley Interdisciplinary Reviews: Developmental Biology, 4(5), 545-554. [PDF] [Link]